article-journal

Exosomal long noncoding RNA MLETA1 promotes tumor progression and metastasis by regulating the miR-186-5p/EGFR and miR-497-5p/IGF1R axes in non-small cell lung cancer
Background:
Lung cancer is the most common and deadliest cancer worldwide, and approximately 90% of all lung cancer deaths are caused …
Xiu‑Rui Hsu, Jia‑En Wu, Yi‑Ying Wu, Sheng‑Yen Hsiao, Jui‑Lin Liang, Ya‑Ju Wu, *Chia-Hao Tung*, Meng‑Fan Huang, Ming‑Shiu Lin, Pan‑Chyr Yang, Yuh‑Ling Chen#, Tse‑Ming Hong#
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Exosomal long noncoding RNA MLETA1 promotes tumor progression and metastasis by regulating the miR-186-5p/EGFR and miR-497-5p/IGF1R axes in non-small cell lung cancer
Ubiquitin-specific peptidase 5 facilitates cancer stem cell-like properties in lung cancer by deubiquitinating β-catenin
Background:
Lung cancer has the highest mortality rate in the world, and mounting evidence suggests that cancer stem cells (CSCs) are …
*Chia-Hao Tung*, Jia-En Wu, Meng-Fan Huang, Wen-Lung Wang, Yi-Ying Wu, Yao-Tsung Tsai, Xiu-Rui Hsu, Sheng-Hsiang Lin, Yuh-Ling Chen, Tse-Ming Hong
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Ubiquitin-specific peptidase 5 facilitates cancer stem cell-like properties in lung cancer by deubiquitinating β-catenin
MiR-455-5p suppresses PDZK1IP1 to promote the motility of oral squamous cell carcinoma and accelerate clinical cancer invasion by regulating partial epithelial-to-mesenchymal transition
Background:
Lymph node and distant metastasis contribute to poor outcomes in patients with oral squamous cell carcinoma (OSCC). The …
Sheng-Yen Hsiao, Shang-Mei Weng, Jenn-Ren Hsiao, Jia‑En Wu, Yi‑Ying Wu, *Chia-Hao Tung*, Wan-Lin Shen, Shu-Fang Sun, Wen-Tsung Huang, Cheng-Yao Lin, Shang-Hung Chen, Yuh‑Ling Chen#, Tse‑Ming Hong#, Jang-Yang Chang#
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MiR-455-5p suppresses PDZK1IP1 to promote the motility of oral squamous cell carcinoma and accelerate clinical cancer invasion by regulating partial epithelial-to-mesenchymal transition
A novel DNA aptamer targeting lung cancer stem cells exerts a therapeutic effect by binding and neutralizing Annexin A2
Cancer remains one of the leading causes of death worldwide. Cancer stem cells (CSCs) are the underlying reason for tumor recurrence, …
Yi‑Ying Wu, I-Shan Hsieh, *Chia-Hao Tung*, Chen-Hsun Weng, Jia‑En Wu, Jau-Song Yu, Yuh‑Ling Chen#, Tse‑Ming Hong#
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A novel DNA aptamer targeting lung cancer stem cells exerts a therapeutic effect by binding and neutralizing Annexin A2
α-Catulin promotes cancer stemness by antagonizing WWP1-mediated KLF5 degradation in lung cancer

Background:
The cytoskeletal linker protein α-Catulin has been shown to be important for tumor progression in various cancers. However, …
*Chia-Hao Tung*, Meng-Fan Huang, Chen-Hsien Liang, Yi-Ying Wu, Jia-En Wu, Cheng-Lung Hsu, Yuh-Ling Chen#, Tse-Ming Hong#
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α-Catulin promotes cancer stemness by antagonizing WWP1-mediated KLF5 degradation in lung cancer
DNA methylation maintains the CLDN1-EPHB6-SLUG axis to enhance chemotherapeutic efficacy and inhibit lung cancer progression

Background:
The loss of cancer-cell junctions and escape from the primary-tumor microenvironment are hallmarks of metastasis. A …
Jia-En Wu, Yi-Ying Wu, *Chia-Hao Tung*, Yao-Tsung Tsai, Hsuan-Yu Chen, Yuh-Ling Chen#, Tse-Ming Hong#
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DNA methylation maintains the CLDN1-EPHB6-SLUG axis to enhance chemotherapeutic efficacy and inhibit lung cancer progression
A DNA Aptamer targeting galectin-1 as a novel immunotherapeutic strategy for lung cancer
Galectin-1 (Gal-1) is a pleiotropic homodimeric β-galactoside-binding protein with a single carbohydrate recognition domain. It has …
Yao-Tsung Tsai, Chen-Hsien Liang, Jin-Hsuan Yu, Kuan-Chih Huang, *Chia-Hao Tung*, Jia-En Wu, Yi-Ying Wu, Chih-Hsien Chang, Tse-Ming Hong#, Yuh-Ling Chen#
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A DNA Aptamer targeting galectin-1 as a novel immunotherapeutic strategy for lung cancer
MicroRNA-150-5p promotes cell motility by inhibiting c-Myb-mediated Slug suppression and is a prognostic biomarker for recurrent ovarian cancer
Treatment of ovarian cancer (OvCa) remains challenging owing to its high recurrence rates. Detachment of cancer cells into the …
*Chia-Hao Tung*, Meng-Fan Huang, Li-Wei Kuo, Yi-Ying Wu, Yao-Tsung Tsai, Jia-En Wu, Keng-Fu Hsu, Yuh-Ling Chen#, Tse-Ming Hong#
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MicroRNA-150-5p promotes cell motility by inhibiting c-Myb-mediated Slug suppression and is a prognostic biomarker for recurrent ovarian cancer
CASZ1 is a novel promoter of metastasis in ovarian cancer
Epithelial ovarian cancer (EOC) carries the highest mortality rate of all gynecologic malignancies. This high mortality rate is …
Yi-Ying Wu, Chia-Lin Chang, Yuan-Jhe Chuang, Jia-En Wu, *Chia-Hao Tung*, Yeong-Chang Chen, Yuh-Ling Chen, Tse-Ming Hong, Keng-Fu Hsu#
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