About me
I’m now a Postdoctoral Scholar of Genome Sciences at University of Washington. I’m currently studying the extrachromosomal DNA-chromatin interactions using 3D genome conformation assays, such as ChIA-PET and ChIA-Drop, and integrate these data with Cut & Tag, ChIP-seq and RNA-seq.
Interests
- Cancer Biology
- Translational Medicine
- Genomics
- Computational Biology
Education
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Ph.D. in Basic Medical Sciences, 2019
National Cheng Kung University, Taiwan
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M.S. in Clinical Medicine, 2011
National Cheng Kung University, Taiwan
Experience
Postdoctoral Scholar, Department of Genome Sciences
- Supervised by Chia-Lin Wei, PhD
- Research focus: Decoding the impact of Extrachromosomal DNA (ecDNA) condensates in cancer
Postdoctoral Associate, Genome Technologies R&D
The Jackson Laboratory
Postdoctoral fellow, Institute of Clinical Medicine
National Cheng Kung University
- Supervised by Tse-Ming Hong, PhD
- Deciphering the role of α-Catulin in lung cancer stemness
- Investigating the clinical relevance of deubiquitinase USP5 in lung cancer stemness
- Identification and investigation of long non-coding RNAs (lncRNAs) in regulating the stemness properties of lung cancer
- Study of the clinical assciation between lncRNAs and cancer stemness pathways in lung cancer using bioinformatic analysis
Recent Publications
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(2023).
Exosomal long noncoding RNA MLETA1 promotes tumor progression and metastasis by regulating the miR-186-5p/EGFR and miR-497-5p/IGF1R axes in non-small cell lung cancer.
Journal of Experimental & Clinical Cancer Research, 42.
(2023).
Ubiquitin-specific peptidase 5 facilitates cancer stem cell-like properties in lung cancer by deubiquitinating β-catenin.
Cancer Cell International, 23.
(2023).
MiR-455-5p suppresses PDZK1IP1 to promote the motility of oral squamous cell carcinoma and accelerate clinical cancer invasion by regulating partial epithelial-to-mesenchymal transition.
Journal of Experimental & Clinical Cancer Research, 42.
(2022).
A novel DNA aptamer targeting lung cancer stem cells exerts a therapeutic effect by binding and neutralizing Annexin A2.
Molecular Therapy-Nucleic Acids, 27.
(2022).
α-Catulin promotes cancer stemness by antagonizing WWP1-mediated KLF5 degradation in lung cancer.
Theranostics, 12.
(2020).
DNA methylation maintains the CLDN1-EPHB6-SLUG axis to enhance chemotherapeutic efficacy and inhibit lung cancer progression.
Theranostics, 10.
(2019).
A DNA Aptamer targeting galectin-1 as a novel immunotherapeutic strategy for lung cancer.
Molecular Therapy-Nucleic Acids, 18.
(2019).
MicroRNA-150-5p promotes cell motility by inhibiting c-Myb-mediated Slug suppression and is a prognostic biomarker for recurrent ovarian cancer.
Oncogene, 39.
(2016).
CASZ1 is a novel promoter of metastasis in ovarian cancer.
American journal of cancer research, 6.
CV
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Contact
- chtung0128@gmail.com
- 3720 15th Ave NE, Seattle, WA 98195-5065
- Enter Foege Building and take the stairs to Office S213D on Floor 2
- Monday - Friday 10:00 to 16:00
- DM Me